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Future research must prioritize the identification of these core genetic and environmental signatures and elucidate how they contribute to the transition from precancerous conditions to invasive cancer
165 APOE is a lipid and cholesterol transporter with numerous CNS-related functions, including regulation of microglial and astrocytic functions, 100,166,167 cerebrovascular integrity, 168 BBB integrity, 169,170 myelin dynamics, 166,171 and neuronal network activity
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Temperature excursions: what happens when storage goes wrong Life is not a laboratory
Although cystine starvation has been shown to induce oxidative stress, we did not observe any increase in soluble or lipid ROS production in cystine-starved cells (Fig
